The Navigator - Navigenics Blog

Genetic insights into health and wellness

December 15, 2008

In prostate cancer prevention, vitamins are no magic bullet

Michael Nierenberg, M.D.,

Navigenics Medical Director

Posted 10:02 AM PDT

imageThe health community was energized in recent years when research hinted that basic vitamins might ward off prostate cancer. Prevention in a bottle? What could be better than that?

Well, lots of things, actually.

As it turns out, recent studies are finding that dietary supplements such as vitamin E and selenium won’t stave off the common cancer. One study of 300,000 men even found those who took more than seven multivitamins a week were more likely to develop an aggressive prostate cancer – and had twice the risk of dying from the disease.

Other recent research echoes these findings. A much anticipated large-scale federal trial of selenium and vitamin E supplements found they do not prevent prostate cancer, and could potentially be harmful. Researchers noted that men over age 50 who were taking vitamin E were slightly more likely to develop prostate cancer. And those who took selenium had higher rates of type 2 diabetes.

“As we continue to monitor the health of these 35,000 men, this information may help us understand why two nutrients that showed strong initial evidence to be able to prevent prostate cancer did not do so,” said researcher Dr. Eric Klein in a written statement.

While dietary supplements now appear to be largely ineffective at prostate cancer prevention, there are many proven and promising measures men can take to reduce their risk of developing the disease. They include:

  • Getting screened annually, including a digital rectal examination and PSA test
  • Maintaining a healthy weight
  • Consuming less red meat and more fruits and vegetables
  • Exercising regularly
  • Avoiding supplemental testosterone and muscle-building steroids
  • Finasteride and statins are drugs which may possibly play a preventive role in prostate cancer, but like all drugs have side effects and should be considered only after a consultation with your physician.  The studies on these drugs are confusing and do not demonstrate a clear benefit.

Genetics account for nearly half the risk of prostate cancer. A Navigenics genetic test can help define one’s genetic risk for prostate cancer. This data may help your physiacian and you determine at what age to start screening for prostate cancer.  Knowing from such a test that you have a genetic predisposition to the condition may be the motivation you need to make positive lifestyle changes that boost overall health. Exercising, eating right and keeping your weight at normal levels may not be as easy as popping a vitamin, but are more beneficial – not only to prostate health, but to your general well-being.

Categories: Prevention

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1 Comment

Jonsan Feb 26, 2009

Nice blog .....

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