The Navigator - Navigenics Blog

Genetic insights into health and wellness

All posts authored by Jennifer Wessel

August 04, 2008

An even better gauge for breast cancer risk

Jennifer Wessel,

Senior Genetic Epidemiologist

Posted 02:00 PM PDT

Common genetic variants and the role they play in breast cancer have been popular topics in scientific journals lately.  I recently mentioned a new study in the New England Journal of Medicine that found women with 14 of the genetic markers associated with breast cancer had 6.3 times the risk of breast cancer as women with none of the markers.  “A few susceptibility alleles may distinguish women who are at high risk for breast cancer from those who are at low risk,” the study determined.

Now comes more research that supports the notion that analyzing a woman’s genes can be a useful weapon to add to the arsenal physicians and patients have in the battle against breast cancer.

Scientists had already established that there are several environmental links to breast cancer, including a woman’s age at first period, her family history and current age. Recently, researchers have had the tools to start identifying the other pieces of the puzzle – genetic risk factors. 

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Categories: About Navigenics, Breast cancer, Genetic research

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July 10, 2008

New study brings genes into breast cancer detection

Jennifer Wessel,

Senior Genetic Epidemiologist

Posted 09:40 AM PDT

imageIf you’re a woman in your 20s or 30s, you probably haven’t had a mammogram. The people who calculate the need for medical tests figure it’s not worth it to screen most women at such a relatively young age.

But if you already knew, from your genes, that you were at elevated risk for breast cancer, you might feel differently. Now, some researchers feel differently about it too.

Researchers at the University of Cambridge found that women with 14 of the genetic markers associated with increased risk of breast cancer had about six times the risk of breast cancer as women with none of the markers. They recently reported their findings in the New England Journal of Medicine.

Their research could mean a big change in the timing of cancer screening for some women, as well as the ways doctors detect early signs of the disease.

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Categories: About Navigenics, Breast cancer

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